Practical and Convenient Suzuki-Miyaura Coupling Reaction and α-Arylation Using Diphenylcyclopropylphosphine Ligands.

A new ligand, diphenylmethylcyclopropylphosphine, has successfully been applied in the palladium-catalyzed Suzuki-Miyaura coupling and α-arylation of ketones with aryl chlorides in moderate to high yields. An asymmetric coupling between anisyl chloride and 2-methylindan-1-one was also tested as the first trial, giving 80% yield and 41% ee with 1 mol% of Pd. [ABSTRACT FROM AUTHOR]