Synthesis of a Novel Tetrahydroxylated β-Homoproline.

A gram-scale synthesis of a novel densely functionalized and orthogonally protected β-homoproline was achieved from l-tartaric acid derived nitrone through a highly stereoselective 1,3-�dipolar cycloaddition to γ-crotonolactone as the key initial step, followed by appropriate elaboration of the adduct. [ABSTRACT FROM AUTHOR]