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Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in...
- Source :
-
Cell . 7/28/95, Vol. 82 Issue 2, p309. 11p. 4 Color Photographs, 12 Black and White Photographs, 2 Diagrams, 1 Chart. - Publication Year :
- 1995
-
Abstract
- Focuses on the defective DNA mismatch repair gene PMS2 in male mice. Analysis of axial element and synaptonemal complex formation; Effect of DNA mismatch repair proteins on mutation reduction and genetic recombination; Association of PMS2 deficiency with male sterility and abnormal spermatogenesis; Meiotic studies of PMS2-deficient males.
- Subjects :
- *DNA ligases
*LABORATORY mice
*CHROMOSOME abnormalities
*PMS genes
Subjects
Details
- Language :
- English
- ISSN :
- 00928674
- Volume :
- 82
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- 9508235643
- Full Text :
- https://doi.org/10.1016/0092-8674(95)90318-6