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Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation.

Authors :
Zhou, Yu
Wang, Yanchun
Wang, Jian
Anne Stetler, R.
Yang, Qing-Wu
Source :
Progress in Neurobiology. Apr2014, Vol. 115, p25-44. 20p.
Publication Year :
2014

Abstract

Highlights: [•] RBC lysis aggravates ICH-induced inflammatory injury through TLR signaling. [•] Molecules released from dead cells mediate ICH-induced inflammatory injury. [•] Multiple inflammatory pathways are therapeutic targets for treating ICH. [•] TLR signaling may provide novel therapeutic targets for the treatment of ICH. [•] Researches on ICH pathogenesis will help to identify novel therapeutic targets. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*INFLAMMATION
*INTRACEREBRAL hematoma
*CEREBRAL hemorrhage
*OCULAR injuries
*CELL death

Details

Language :
English
ISSN :
03010082
Volume :
115
Database :
Academic Search Index
Journal :
Progress in Neurobiology
Publication Type :
Academic Journal
Accession number :
95021442
Full Text :
https://doi.org/10.1016/j.pneurobio.2013.11.003
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