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Polychlorinated biphenyl quinone-induced genotoxicity, oxidative DNA damage and γ-H2AX formation in HepG2 cells.
- Source :
-
Chemico-Biological Interactions . Apr2014, Vol. 212, p47-55. 9p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] PCB quinone is genotoxic positive to HepG2 cells. [•] PCB quinone exposure causes increasing of DNA breaks and micronuclei. [•] PCB quinone induced 8-OHdG formation. [•] PCB quinone induced γ-H2AX expression. [•] ROS scavengers inhibited the genotoxicity of PCB quinone. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00092797
- Volume :
- 212
- Database :
- Academic Search Index
- Journal :
- Chemico-Biological Interactions
- Publication Type :
- Academic Journal
- Accession number :
- 95021230
- Full Text :
- https://doi.org/10.1016/j.cbi.2014.01.016