Interactive effects of CO2 and trace metals on the proteasome activity and cellular stress response of marine bivalves Crassostrea virginica and Mercenaria mercenaria.

Highlights: [•] Elevated enhanced accumulation of Cu and Cd in the gills of mollusks. [•] The proteasome activities were affected by metals but robust to elevated . [•] Exposure to Cd and Cu had opposite effects on the proteasome activity. [•] Combined exposure to Cu and elevated negatively affected energy status. [ABSTRACT FROM AUTHOR]