Dose scaling for the morbidly obese.

The article focuses on dose scaling in anaesthesia for the morbidly obese. Topics discussed include impact of linear dosing according to total body weight results in overdosing the obese and underdosing small children, the study "Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model" by LI Cortinez and others and use of using dual-energy X-ray absorptiometry for measurement of fat-free mass. Also discusses the allometric scaling as an alternate method.