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Modulation of oxidative stress and Ca2+ mobilization through TRPM2 channels in rat dorsal root ganglion neuron by Hypericum perforatum.
- Source :
-
Neuroscience . Mar2014, Vol. 263, p27-35. 9p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] Oxidative stress and Ca2+ influx play an important role in pain. [•] Effects of H. perforatum (HP) on Ca2+ and apoptosis in the DRG were investigated. [•] Ca2+ influx through TRPM2 channel in the DRG neuron is high. [•] HP modulated oxidative stress and Ca2+ influx in the DRG. [•] The study is the first to compare effects of HP on TRPM2 channels in the DRG. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 03064522
- Volume :
- 263
- Database :
- Academic Search Index
- Journal :
- Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 94696755
- Full Text :
- https://doi.org/10.1016/j.neuroscience.2014.01.006