Land use regression models as a tool for short, medium and long term exposure to traffic related air pollution.

Abstract: Background and aims: In the HEAPS (Health Effects of Air Pollution in Antwerp Schools) study the importance of traffic-related air pollution on the school and home location on children's health was assessed. 130 children (aged 6 to 12) from two schools participated in a biomonitoring study measuring oxidative stress, inflammation and cardiovascular markers. Methods: Personal exposure of schoolchildren to black carbon (BC) and nitrogen dioxide (NO2) was assessed using both measured and modeled concentrations. Air quality measurements were done in two seasons at approximately 50 locations, including the schools. The land use regression technique was applied to model concentrations at the children's home address and at the schools. Results: In this paper the results of the exposure analysis are given. Concentrations measured at school 2h before the medical examination were used for assessing health effects of short term exposure. Over two seasons, this short term BC exposure ranged from 514ng/m3 to 6285ng/m3, and for NO2 from 11μg/m3 to 36μg/m3. An integrated exposure was determined until 10days before the child's examination, taking into account exposures at home and at school and the time spent in each of these microenvironments. Land use regression estimates were therefore recalculated into daily concentrations by using the temporal trend observed at a fixed monitor of the official air quality network. Concentrations at the children's homes were modeled to estimate long term exposure (from 1457ng/m3 to 3874ng/m3 for BC; and from 19μg/m3 to 51μg/m3 for NO2). Conclusions: The land use regression technique proved to be a fast and accurate means for estimating long term and daily BC and NO2 exposure for children living in the Antwerp area. The spatial and temporal resolution was tailored to the needs of the epidemiologists involved in this study. [Copyright &y& Elsevier]