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Nuclear Pores Set the Speed Limit for Mitosis.

Authors :
Buchwalter, Abigail
Hetzer, Martin?W.
Source :
Cell. Feb2014, Vol. 156 Issue 5, p868-869. 2p.
Publication Year :
2014

Abstract

The spindle assembly checkpoint prevents separation of sister chromatids until each kinetochore is attached to the mitotic spindle. Rodriguez-Bravo et al. report that the nuclear pore complex scaffolds spindle assembly checkpoint signaling in interphase, providing a store of inhibitory signals that limits the speed of the subsequent mitosis. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00928674
Volume :
156
Issue :
5
Database :
Academic Search Index
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
94687108
Full Text :
https://doi.org/10.1016/j.cell.2014.02.004