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miR-17 inhibitor suppressed osteosarcoma tumor growth and metastasis via increasing PTEN expression.
- Source :
-
Biochemical & Biophysical Research Communications . Feb2014, Vol. 444 Issue 2, p230-234. 5p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] miR-17 was increased in OS tissues and cell lines. [•] Inhibition of miR-17 suppressed OS cell proliferation. [•] Inhibition of miR-17 suppressed OS cell migration and invasion. [•] PTEN was a target of miR-17. [•] miR-17 was negatively correlated with PTEN in OS tissues. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 444
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 94487390
- Full Text :
- https://doi.org/10.1016/j.bbrc.2014.01.061