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Post kala-azar dermal leishmaniasis: an unresolved mystery.

Authors :
Mukhopadhyay, Debanjan
Dalton, Jane E.
Kaye, Paul M.
Chatterjee, Mitali
Source :
Trends in Parasitology. Feb2014, Vol. 30 Issue 2, p65-74. 10p.
Publication Year :
2014

Abstract

Highlights: [•] Sodium antimony gluconate contributes towards the pathogenesis of PKDL. [•] UV light plays a pivotal role in the development of PKDL. [•] Development of PKDL can be viewed as a reinfection or activation of latent Leishmania parasites. [•] PKDL can be resolved by mounting an effective tissue-specific memory T cell response. [•] Host genetic factors play a contributory role. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
14714922
Volume :
30
Issue :
2
Database :
Academic Search Index
Journal :
Trends in Parasitology
Publication Type :
Academic Journal
Accession number :
94151163
Full Text :
https://doi.org/10.1016/j.pt.2013.12.004