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Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro.
- Source :
-
Biochemical & Biophysical Research Communications . Jan2014, Vol. 443 Issue 3, p789-795. 7p. - Publication Year :
- 2014
-
Abstract
- Highlight: [•] MiR-21 plays a significant role in 5-FU resistance. [•] This role might be attributed to targeting of hMSH2 as well as TP and DPD via miR-21 targeted hMSH2. [•] Indirectly targeted TP and DPD to influence 5-FU chemotherapy sensitivity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 443
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 94076216
- Full Text :
- https://doi.org/10.1016/j.bbrc.2013.11.064