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Cooperative interaction of divalent metal ions, substrates, and tissue factor with factor VIIa.

Authors :
Butenas, Saulius
Lawson, Jeffrey H.
Source :
Biochemistry. 3/22/94, Vol. 33 Issue 11, p3449. 6p. 6 Black and White Photographs, 4 Charts, 4 Graphs.
Publication Year :
1994

Abstract

Investigates factor VIIa-tissue factor (TF) complex formation in the presence of ethylene. Enhancement of amidolytic activity of factor VIIa by Me2+; Enhancement by Me2+ in the presence of TF; Enhancement by synthetic substrates in the presence of TF and ethylenediaminetetraacetic acid (EDTA); Apparent dissociation constants for the factor VIIa-TF complex.

Details

Language :
English
ISSN :
00062960
Volume :
33
Issue :
11
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
9406080666
Full Text :
https://doi.org/10.1021/bi00177a039