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Allopregnanolone in the brain: Protecting pregnancy and birth outcomes.

Authors :
Brunton, Paula J.
Russell, John A.
Hirst, Jonathan J.
Source :
Progress in Neurobiology. Feb2014, Vol. 113, p106-136. 31p.
Publication Year :
2014

Abstract

Highlights: [•] Role for central allopregnanolone in reduced neuroendocrine stress responses. [•] Allopregnanolone and oxytocin system interactions for minimising preterm birth risk. [•] Disrupted neurosteroidogenesis in compromised pregnancy and offspring outcomes. [•] Role for progesterone or allopregnanolone in correcting adverse pregnancy outcomes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03010082
Volume :
113
Database :
Academic Search Index
Journal :
Progress in Neurobiology
Publication Type :
Academic Journal
Accession number :
94051875
Full Text :
https://doi.org/10.1016/j.pneurobio.2013.08.005