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Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice.
- Source :
-
Science . 11/5/1993, Vol. 262 Issue 5135, p907. 3p. 3 Black and White Photographs, 3 Graphs. - Publication Year :
- 1993
-
Abstract
- Examines how the interaction between CD28 and B7 results in interleukin-2 secretion and T cell proliferation. Evaluation of B7 role in vivo; Demonstration of existence of alternative CTLA-4 ligands through activated mouse B cells; Effect of CTLA-4 ligands on allogenic mixed lymphocyte responses.
- Subjects :
- *LIGANDS (Biochemistry)
*B cells
*T cells
*SCIENTIFIC experimentation
Subjects
Details
- Language :
- English
- ISSN :
- 00368075
- Volume :
- 262
- Issue :
- 5135
- Database :
- Academic Search Index
- Journal :
- Science
- Publication Type :
- Academic Journal
- Accession number :
- 9403031314
- Full Text :
- https://doi.org/10.1126/science.7694362