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Block of cardiac ATP-sensitive K+ channels by external divalent cations is modulated by...

Authors :
Kwok, Wai-Meng
Kass, Robert S.
Source :
Journal of General Physiology. Oct93, Vol. 102 Issue 4, p693. 20p. 18 Graphs.
Publication Year :
1993

Abstract

Investigates the interactions between extracellular divalent cations and the adenosine triphosphatase-sensitive potassium channel. Blocking of current by extracellularly applied cobalt, cadmium and zinc cations; Concentrations; Whole-cell patch clamping conditions; Dependency of blockage on intracellular ATP concentrations; Conformational change of channel protein.

Details

Language :
English
ISSN :
00221295
Volume :
102
Issue :
4
Database :
Academic Search Index
Journal :
Journal of General Physiology
Publication Type :
Academic Journal
Accession number :
9403030723
Full Text :
https://doi.org/10.1085/jgp.102.4.693