Contribution of growth hormone and IGF-I to early diabetic nephropathy in type 1 diabetes.

Authors :: Cummings, Elizabeth A.
Sochett, Etienne B.
Dekker, M.G.
Lawson, M.L.
Daneman, D.
Source :: Diabetes. Aug1998, Vol. 47 Issue 8, p1341. 6p. 2 Charts, 5 Graphs.
Publication Year :: 1998
Abstract: Examines the relationship of growth hormone (GH), insulin-like growth factor-I (IGF-I), testosterone and prorenin to kidney volume (KV) and microalbuminuria (MA) in subjects with similar diabetes duration. Strong association of urinary IGF-I with KV, a marker for glomerular hypertrophy; Role of GH and IGF-I to the pathogenesis of diabetic nephropathy.

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