Two new compounds from the fungus Penicillium crustosum YN-HT-15.

Our current natural product program researches the second metabolites of a fungus Penicilliumcrustosum YN-HT-15 isolated from the red soil (Yunnan Province, China), to discover potential antitumor chemical entities. Two new compounds were isolated from the ethyl acetate extract of the fermentation broth of the fungus, and their structures were characterized as 1-(2′,4′-dihydroxy-5′-methyl-3′-methylsulfanylmethyl-phenyl)-ethanone (1) and R-3-(3′-acetyl-2′,6′-dihydroxy-5′-methylphenyl)-2-methyl-propionic acid methyl ester (2) on the basis of spectroscopic data. [ABSTRACT FROM AUTHOR]