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Ether bridge formation in loline alkaloid biosynthesis.

Authors :
Pan, Juan
Bhardwaj, Minakshi
Faulkner, Jerome R.
Nagabhyru, Padmaja
Charlton, Nikki D.
Higashi, Richard M.
Miller, Anne-Frances
Young, Carolyn A.
Grossman, Robert B.
Schardl, Christopher L.
Source :
Phytochemistry. Feb2014, Vol. 98, p60-68. 9p.
Publication Year :
2014

Abstract

Highlights: [•] Genomes were sequenced for four fungi with three different loline alkaloid profiles. [•] Different loline alkaloid profiles were associated with differences in loline alkaloid biosynthesis gene clusters. [•] The LolO non-heme iron oxygenase is required for loline ether bridge formation. [•] An exo-1-acetamidopyrrolizidine is a likely pathway intermediate in loline alkaloid biosynthesis. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00319422
Volume :
98
Database :
Academic Search Index
Journal :
Phytochemistry
Publication Type :
Academic Journal
Accession number :
93701111
Full Text :
https://doi.org/10.1016/j.phytochem.2013.11.015