Quantitative analysis of visible surface defect risk in tablets during film coating using terahertz pulsed imaging.

Highlights: [•] TPI could provide spatial distribution of surface density/roughness of core tablet. [•] Tensile strength, friability provided no information on visible surface defect risk. [•] TPI helped in estimating tablet abrasion risk prior to film coating. [•] TPI revealed the relationship between surface strength and blending condition. [Copyright &y& Elsevier]