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Knockdown of p53 suppresses Nanog expression in embryonic stem cells.
- Source :
-
Biochemical & Biophysical Research Communications . Jan2014, Vol. 443 Issue 2, p652-657. 6p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] We investigate the role of p53 in ESCs in the absence of DNA damage. [•] p53 knockdown suppresses ESC proliferation. [•] p53 knockdown downregulates Nanog expression. [•] p53 is essential for mouse ESC self-renewal. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 443
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 93655262
- Full Text :
- https://doi.org/10.1016/j.bbrc.2013.12.030