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Measurement of HMG CoA reductase activity in different human cell lines by ultra-performance liquid chromatography tandem mass spectrometry.

Authors :
Kuzaj, Patricia
Kuhn, Joachim
Faust, Isabel
Knabbe, Cornelius
Hendig, Doris
Source :
Biochemical & Biophysical Research Communications. Jan2014, Vol. 443 Issue 2, p641-645. 5p.
Publication Year :
2014

Abstract

Highlights: [•] We developed a fast, sensitive, and efficient method to determine HMGCR activity in different human cell lines. [•] MVL levels were determined using UPLC–MS/MS. [•] Lower limit of quantification was 0.12μg/l. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0006291X
Volume :
443
Issue :
2
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
93655260
Full Text :
https://doi.org/10.1016/j.bbrc.2013.12.013