Back to Search
Start Over
Atenolol use is associated with long-term mortality in community-dwelling older adults with hypertension.
- Source :
-
Geriatrics & Gerontology International . Jan2014, Vol. 14 Issue 1, p153-158. 6p. - Publication Year :
- 2014
-
Abstract
- Aim The role of atenolol, a non-vasodilating beta-blocker drug, on long-term mortality in hypertensive older adults is still unclear. The aim of the present study was to evaluate long-term mortality in community-dwelling hypertensive older adults taking atenolol. Methods Long-term mortality after 12-year follow up in isolated hypertensive older adults ( n = 972) was analyzed. The patients were stratified in the presence and absence of atenolol use. Systolic, diastolic and pulse arterial pressure were measured. Results Older adults taking atenolol showed a greater mortality and higher pulse arterial pressure values than those not taking atenolol (73.9% vs 55.0%; P = 0.047 and 74.7 ± 14.1 vs 63.0 ± 14.2 mmHg, P < 0.001, respectively). Cox regression analysis showed that atenolol use (hazard risk 1.91; 95% confidence interval 1.04-4.31; P = 0.04) and pulse arterial pressure (hazard risk 1.02; 95% confidence interval 1.01-1.03; P = 0.032) were predictive of long-term mortality. Conclusions Atenolol use was related to increased mortality in community-dwelling hypertensive Older adults. This increase in mortality risk seems to be related to an increase of pulse arterial pressure. Geriatr Gerontol Int 2014; 14: 153-158. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ARTERIAL physiology
*ANALYSIS of variance
*ATENOLOL
*BLOOD pressure
*BLOOD pressure measurement
*CHI-squared test
*CONFIDENCE intervals
*HYPERTENSION
*NEUROPSYCHOLOGICAL tests
*PROBABILITY theory
*PULSE (Heart beat)
*INDEPENDENT living
*CROSS-sectional method
*GERIATRIC Depression Scale
*DATA analysis software
*DESCRIPTIVE statistics
MORTALITY risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 14441586
- Volume :
- 14
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Geriatrics & Gerontology International
- Publication Type :
- Academic Journal
- Accession number :
- 93594578
- Full Text :
- https://doi.org/10.1111/ggi.12073