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Value of MRI for the diagnosis of cardiac involvement in sarcoidosis

Value of MRI for the diagnosis of cardiac involvement in sarcoidosis

Authors :
Dhôte, R.
Vignaux, O.
Blanche, P.
Duboc, D.
Dusser, D.
Brezin, A.
Devaux, J.-Y.
Christoforov, B.
Legmann, P.
Source :
Revue de Médecine Interne. Mar2003, Vol. 24 Issue 3, p151. 7p.
Publication Year :
2003

Abstract

Purpose. – The aim of the study was to assess the place of cardiac Magnetic Resonance Imaging (MRI) in patients with sarcoidosis with or without cardiac involvement.Material and methods. – Fifty patients with histologically-proven sarcoidosis underwent initial cardiac evaluation including MRI, ECG, holter ECG, echocardiography. Seven of them had cardiac involvement (cardiac insufficiency, auriculo-ventricular block, bundle-branch block). Fiveteen patients had a second evaluation at 10-month follow-up. MRI was classified in three stages, on the base of literature data (stage 1 “granulomatous”, stage 2 “exsudative”, stage 3 “fibrotic”).Results. – A good correlation between the type of the sarcoidosis and MRI was observed: patients with cardiac involvement had all stage 2 MRI; patients with quiescent sarcoidosis had normal or stage 3 MRI; patients without cardiac involvement had all stages on MRI. A good correlation was observed between cardiac MRI abnormalities and evolution of sarcoidosis. Patients under corticoid, with or without cardiac involvement all had regression of MRI lesions and sarcoidosis. In 2 cases, MRI was predictive of clinical cardiac involvement.Conclusion. – Cardiac MRI is a useful non-invasive method for the early diagnosis and follow-up of cardiac sarcoidosis. [Copyright &y& Elsevier]

Details

Language :
French
ISSN :
02488663
Volume :
24
Issue :
3
Database :
Academic Search Index
Journal :
Revue de Médecine Interne
Publication Type :
Academic Journal
Accession number :
9343092
Full Text :
https://doi.org/10.1016/S0248-8663(02)00808-1