ChemInform Abstract: Cu-Mediated 1,3-Dipolar Cycloaddition of Azomethine Ylides with Dipolarophiles: A Faster Access to Spirooxindoles of Potential Pharmacological Interest.

Authors :: Singh, Shambhu Nath
Regati, Sridhar
Paul, Abir Kumar
Layek, Mohosin
Jayaprakash, Sarva
Reddy, K. Venkateshwara
Deora, Girdhar Singh
Mukherjee, Soumita
Pal, Manojit
Source :: ChemInform. Jan2014, Vol. 45 Issue 4, pno-no. 1p.
Publication Year :: 2014
Abstract: The first Cu-mediated one-pot three-component reaction of isatin derivatives (I), L-proline (II), and terminal alkynes (III) leading to spiropyrrolidine oxindols (IV) is reported. [ABSTRACT FROM AUTHOR]

Subjects :: *COPPER compounds
*ZWITTERIONS
*RING formation (Chemistry)
*SCHIFF bases
*OXINDOLES
*INDOLE compounds
*ENZYME activation

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