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Epstein-Barr Virus and Human Herpesvirus 6 Detection in a Non- Hodgkin's Diffuse Large B-Cell Lymphoma Cohort by Using RNA Sequencing.
- Source :
-
Journal of Virology . Dec2013, Vol. 87 Issue 23, p13059-13062. 4p. - Publication Year :
- 2013
-
Abstract
- Comprehensive virome analysis of RNA sequence (RNA-seq) data sets from 118 non-Hodgkin's B-cell lymphomas revealed a small subset that is positive for Epstein-Barr virus (EBV) or human herpesvirus 6B (HHV-6B), with one coinfection. EBV transcriptome analysis revealed expression of the latency genes RPMS1, LMP1, and LMP2, with one sample additionally showing a high level of early lytic expression and another sample showing a high level of EBNA2 expression. HHV-6B transcriptome analysis revealed that the majority of genes were transcribed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0022538X
- Volume :
- 87
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Journal of Virology
- Publication Type :
- Academic Journal
- Accession number :
- 93394797
- Full Text :
- https://doi.org/10.1128/JVI.02380-13