Back to Search
Start Over
Coffee, tea, and the risk of hip fracture: a meta-analysis.
- Source :
-
Osteoporosis International . Jan2014, Vol. 25 Issue 1, p141-150. 10p. 2 Diagrams, 2 Charts, 1 Graph. - Publication Year :
- 2014
-
Abstract
- Summary: The present meta-analysis shows no clear association between coffee consumption and the risk of hip fractures. There was a nonlinear association between tea consumption and the risk of hip fracture. Compared to no tea consumption, drinking 1−4 cups of tea daily was associated with a lower risk of hip fracture. Introduction: Prospective cohort and case-control studies have suggested that coffee and tea consumption may be associated with the risk of hip fracture; the results have, however, been inconsistent. We conducted a meta-analysis to assess the association between coffee and tea consumption and the risk of hip fracture. Methods: We performed systematic searches using MEDLINE, EMBASE, and OVID until February 20, 2013, without limits of language or publication year. Relative risks (RRs) with 95 % confidence intervals (CI) were derived using random-effects models throughout all analyses. We conducted categorical, dose-response, heterogeneity, publication bias, and subgroup analyses. Results: Our study was based on 195,992 individuals with 9,958 cases of hip fractures from 14 studies, including six cohort and eight case-control studies. The pooled RRs of hip fractures for the highest vs. the lowest categories of coffee and tea consumption were 0.94 (95 % CI 0.71-1.17) and 0.84 (95 % CI 0.66-1.02), respectively. For the dose-response analysis, we found evidence of a nonlinear association between tea consumption and the risk of hip fracture ( p < 0.01). Compared to no tea consumption, 1-4 cups of tea per day may reduce the risk of hip fracture by 28 % (0.72; 95 % CI 0.56-0.88 for 1-2 cups/day), 37 % (0.63; 95 % CI 0.32-0.94 for 2-3 cups/day), and 21 % (0.79; 95 % CI 0.62-0.96 for 3-4 cups/day). Conclusions: We found no significant association between coffee consumption and the risk of hip fracture. A nonlinear association emerged between tea consumption and the risk of hip fracture; individuals drinking 1-4 cups of tea per day exhibited a lower risk of hip fractures than those who drank no tea. The association between 5 daily cups of tea, or more, and hip fracture risk should be investigated. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RISK factors of fractures
*HIP joint injuries
*COFFEE
*CONFIDENCE intervals
*DATABASES
*DOSE-response relationship in biochemistry
*EPIDEMIOLOGY
*MEDICAL information storage & retrieval systems
*LONGITUDINAL method
*MEDLINE
*META-analysis
*REGRESSION analysis
*RESEARCH funding
*STATISTICS
*TEA
*SYSTEMATIC reviews
*DATA analysis
*RELATIVE medical risk
*DATA analysis software
*DESCRIPTIVE statistics
*INJURY risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 0937941X
- Volume :
- 25
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Osteoporosis International
- Publication Type :
- Academic Journal
- Accession number :
- 93392674
- Full Text :
- https://doi.org/10.1007/s00198-013-2563-7