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Distraction chondroneogenesis on rabbit's ear cartilage.

Authors :
DURMUŞ KOCAASLAN, Fatma Nihal
ÇELEBİLER, Özhan
NUMANOĞLU, Ayhan
TÜRKÖZ, Hüseyin Kemal
Source :
Marmara Medical Journal. 2013, Vol. 26 Issue 3, p136-141. 6p.
Publication Year :
2013

Abstract

Objective: Application of distraction is an alternative to bone graft or flap operations for repairing bone defects. Bone can be extended in width and length without using a new donor area. Operation time is shortened and failures are reduced without any concern about graft or flap loss. However, there are no distraction methods known for generating new cartilage as an alternative to graft or flap applications in repairs of cartilage defects This experimental study was planned to determine whether or not chondroneogenesis can be obtained via application of distraction. Methods: Fourteen New Zealand rabbits were used in this study. Distractions at a rate of 0.50 mm/day, 0.25 mm/day and 0.25 mm on alternate days were applied on 3 rabbits consecutively and the ideal distraction rate was determined as 0.25 mm once every two days. On alternate days 0.25 mm of distraction was applied for two months aiming to generate 7.5 mm of new cartilage. Results: In the rabbits in which 0.25 mm of distraction on alternate days had been applied, regular new cartilage formation was observed. Conclusions: According to these findings, the slow metabolic rate of avascular cartilage tissue affects distraction rates and rhythms. However, by applying distraction and taking advantage of the regenerative capacity of the perichondrium, it is possible to generate new and regular chondrocytes and extend the cartilage. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10191941
Volume :
26
Issue :
3
Database :
Academic Search Index
Journal :
Marmara Medical Journal
Publication Type :
Academic Journal
Accession number :
93390263
Full Text :
https://doi.org/10.5472/MMJ.2013. 02707.1