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Regional and genotypic differences in intrinsic electrophysiological properties of cerebellar Purkinje neurons from wild-type and dystrophin-deficient mdx mice.

Authors :
Snow, Wanda M.
Anderson, Judy E.
Fry, Mark
Source :
Neurobiology of Learning & Memory. Jan2014, Vol. 107, p19-31. 13p.
Publication Year :
2014

Abstract

Highlights: [•] The lack of dystrophin in mdx mice impacts electrophysiology of Purkinje neurons. [•] Purkinje neurons from mdx mice showed reduced spontaneous action potential firing. [•] Intrinsic membrane properties of Purkinje neurons differ between cerebellar regions. [•] Results stress the need to consider cerebellar region in studies of Purkinje neurons. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
10747427
Volume :
107
Database :
Academic Search Index
Journal :
Neurobiology of Learning & Memory
Publication Type :
Academic Journal
Accession number :
93349686
Full Text :
https://doi.org/10.1016/j.nlm.2013.10.017