Neurophysiology of HCN channels: From cellular functions to multiple regulations.

Highlights: [•] Hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels are involved in multiple physiological processes. [•] HCN channels are excellent targets of various cellular signals to finely regulate neuronal responses to external stimuli. [•] Dysregulation of HCN channels is involved in a variety of neurological disorders. [ABSTRACT FROM AUTHOR]