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Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity.
- Source :
-
Neurochemistry International . Jan2014, Vol. 64, p18-23. 6p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] 7,8-DHF as a selective TrkB agonist is neuroprotective. [•] 7,8-DHF has been proved to have antioxidant activity. [•] 7,8-DHF could protect PC12 cells against 6-OHDA-induced toxicity. [•] The protection by 7,8-DHF is due to eliminating ROS and improving SOD activity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01970186
- Volume :
- 64
- Database :
- Academic Search Index
- Journal :
- Neurochemistry International
- Publication Type :
- Academic Journal
- Accession number :
- 93269353
- Full Text :
- https://doi.org/10.1016/j.neuint.2013.10.018