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Regulation of apical transport in epithelial cells by a Gs class of heterotrimeric G protein.

Authors :
Pimplikar, Sanjay W.
Simons, Kai
Source :
Nature. 4/1/1993, Vol. 362 Issue 6419, p456. 3p. 9 Black and White Photographs, 3 Graphs.
Publication Year :
1993

Abstract

Shows that in the epithelial cell line Madin-Darby Canine Kidney (MDCK), transport of influenza hemagglutinin protein (HA) to the apical surface is stimulated and that of vesicular stomatitis virus glycoprotein to the basolateral surface is retarded by AIF treatment. AIF treatment stimulating the HA transport to the apical surface; Pertussis- and cholera toxin-treated MDCK cells; Trans-Golgi network; More.

Subjects

Subjects :
*CYTOLOGICAL research

Details

Language :
English
ISSN :
00280836
Volume :
362
Issue :
6419
Database :
Academic Search Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
9304220045
Full Text :
https://doi.org/10.1038/362456a0