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Endometrial hyperplasia with secretory changes
- Source :
-
Gynecologic Oncology . Mar2003, Vol. 88 Issue 3, p386. 8p. - Publication Year :
- 2003
-
Abstract
- : ObjectiveSecretory changes in endometrial hyperplasia are uncommon. The aim of this study is to review the morphologic and clinical findings of 24 cases of endometrial hyperplasia with secretory changes.: MethodsIn 24 patients diagnosed with endometrial hyperplasia with secretory changes during 6 years, clinical characteristics such as menopausal status and hormone treatment were correlated with morphological features. A matched age control group of 24 women with conventional endometrial hyperplasia was used to compare the hormonal effect.: ResultsNineteen patients were premenopausal. Nine women showed simple hyperplasia without atypia and 15 complex hyperplasia, 7 of them with atypia. Seventeen women were under hormonal treatment at the time of diagnosis, 10 of them with progestins. In 7 patients endometrial adenocarcinoma could be seen, 5 coexisting with endometrial hyperplasia with secretory changes and in 2 appearing after 1 and 4 months. In control group only 2 patients were undergoing progestin hormonal treatment.: ConclusionsSecretory changes can be found in hyperplastic endometrium, particularly in premenopausal women under hormonal treatment with progestins, with the risk of misdiagnosis. [Copyright &y& Elsevier]
- Subjects :
- *HYPERPLASIA
*PROGESTATIONAL hormones
Subjects
Details
- Language :
- English
- ISSN :
- 00908258
- Volume :
- 88
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Gynecologic Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 9291530
- Full Text :
- https://doi.org/10.1016/S0090-8258(02)00140-3