Nano-liposomes as new Drug Delivery Carriers.

Nanoliposomes are colloidal structures composed of a bilayer membrane. In aqueous solutions, hydrophobic phospholipid groups are directed inward sphere, while hydrophilic groups are directed towards the outer sphere. The result of such orientation is formation of two layers composed of lipid molecules. Now-a- day, there have been many efforts to utilize these nano- structures as carriers for drug delivery, gene delivery and modeling of cell membranes in animal and human studies. The ability of encapsulating a large amount of drugs, minimizing unwanted side effects, high efficiency and low toxicity are some of the proper of nano liposomes. For example, the encapsulation of anticancer drugs in such nano-structures have been widely studied. The results showed that using nano- liposomes, delivery to target cells is improved and drug efficacy is increased. The structures of nano-liposomes, the various methods used for preparation and their use as drug delivery carriers are briefly reviewed in this article. [ABSTRACT FROM AUTHOR]