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Water soluble folate-chitosan nanogels crosslinked by genipin.

Authors :
Pujana, Maite Arteche
Pérez-Álvarez, Leyre
Iturbe, L. Carlos Cesteros
Katime, Issa
Source :
Carbohydrate Polymers. Jan2014, Vol. 101, p113-120. 8p.
Publication Year :
2014

Abstract

Highlights: [•] Folate-chitosan nanogels were crosslinked with genipin in microemulsion medium. [•] Nanogels are water soluble at neutral and basic pHs. [•] Degradation rate was slightly higher at endosomic pH 5.5 than at physiological 7.4. [•] Nanogels displayed a pH-responsive release of 5-fluorouracil. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01448617
Volume :
101
Database :
Academic Search Index
Journal :
Carbohydrate Polymers
Publication Type :
Academic Journal
Accession number :
92730933
Full Text :
https://doi.org/10.1016/j.carbpol.2013.09.014