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Efficient synthesis of α-aryl serine derivatives via three-component reactions of aryldiazoacetates, anilines and formaldehyde.
- Source :
-
Tetrahedron . Dec2013, Vol. 69 Issue 52, p11203-11208. 6p. - Publication Year :
- 2013
-
Abstract
- Abstract: A three-component reaction based on trapping of ammonium ylides with formaldehyde was first reported. This reaction offers a new strategy for the synthesis of α-aryl serine derivatives and can be extended to the preparation of α-aryl threonine derivatives. Synthetic application of the three component reaction for the preparation of hydroquinoxaline derivative was also demonstrated. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 69
- Issue :
- 52
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 92715763
- Full Text :
- https://doi.org/10.1016/j.tet.2013.10.046