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Control of vessel sprouting by genetic and metabolic determinants.

Authors :
Eelen, Guy
Cruys, Bert
Welti, Jonathan
De Bock, Katrien
Carmeliet, Peter
Source :
Trends in Endocrinology & Metabolism. Dec2013, Vol. 24 Issue 12, p589-596. 8p.
Publication Year :
2013

Abstract

Highlights: [•] The role of endothelial cell (EC) metabolism in vascular branching is not understood. [•] Vessel branching requires the coordinated action of distinct EC subtypes. [•] PFKFB3-driven glycolysis in ECs determines tip versus stalk cell fate. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10432760
Volume :
24
Issue :
12
Database :
Academic Search Index
Journal :
Trends in Endocrinology & Metabolism
Publication Type :
Academic Journal
Accession number :
92642265
Full Text :
https://doi.org/10.1016/j.tem.2013.08.006