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Proteolytic activity of Plasmodium falciparum subtilisin-like protease 3 on parasite profilin, a multifunctional protein.
- Source :
-
Molecular & Biochemical Parasitology . Oct2013, Vol. 191 Issue 2, p58-62. 5p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] PfSUB3 possesses serine protease activity in its C-terminal region. [•] Plasmodium falciparum profilin interacts with mature PfSUB3. [•] Mature PfSUB3 proteolyses recombinant PfPRF in in vitro assays. [•] PfPRF induces secretion of TNF-α and IL-12 in mouse bone marrow dendritic cells. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01666851
- Volume :
- 191
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Molecular & Biochemical Parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 92640461
- Full Text :
- https://doi.org/10.1016/j.molbiopara.2013.09.006