Preferential suppression of limbic Fos expression by intermittent hypoxia in obese diabetic mice.

Highlights: [•] Brain Fos expression was analyzed in sleep apnea (SA) model using db/db mice. [•] Intermittent hypoxia (IH) reduced Fos expression in the paralimbic cortices. [•] IH also reduced Fos expression in the amygdala, accumbens, ventral tegmental area. [•] Fos expression in the brain stem structures was relatively resistant against IH. [•] Suppression of limbic and paralimbic activities may be linked to central SA symptoms. [ABSTRACT FROM AUTHOR]