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Nanoparticle–DNA–polymer composites for hepatocellular carcinoma cell labeling, sensing, and magnetic resonance imaging.

Authors :
Leung, Ken Cham-Fai
Lee, Siu-Fung
Wong, Chi-Hin
Chak, Chun-Pong
Lai, Josie M.Y.
Zhu, Xiao-Ming
Wang, Yi-Xiang J.
Sham, Kathy W.Y.
Cheng, Christopher H.K.
Source :
Methods. Dec2013, Vol. 64 Issue 3, p315-321. 7p.
Publication Year :
2013

Abstract

Highlights: [•] HepG2 transfection efficacies are studied with MRI, fluorescence and luminescence. [•] Sensing in receptor-mediated endocytosis depends on functional groups of composites. [•] Magnetofection enhances uptake efficacy with at most two orders of magnitude. [•] Cell viabilities of HepG2 and MDCK vary from 70 to 90% with different composites. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
10462023
Volume :
64
Issue :
3
Database :
Academic Search Index
Journal :
Methods
Publication Type :
Academic Journal
Accession number :
92591424
Full Text :
https://doi.org/10.1016/j.ymeth.2013.06.006