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Maternal acrylamide treatment reduces ovarian follicle number in newborn guinea pig offspring.

Authors :
Hułas-Stasiak, Monika
Dobrowolski, Piotr
Tomaszewska, Ewa
Kostro, Krzysztof
Source :
Reproductive Toxicology. Dec2013, Vol. 42, p125-131. 7p.
Publication Year :
2013

Abstract

Highlights: [•] Acrylamide reduces the number of primordial and primary follicles. [•] Acrylamide may disturb the vimentin filament network causing defects in the granulosa cell–oocyte interactions. [•] Acrylamide increases follicular atresia by inducing oocyte apoptosis. [•] Acrylamide does not induce autophagy. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
08906238
Volume :
42
Database :
Academic Search Index
Journal :
Reproductive Toxicology
Publication Type :
Academic Journal
Accession number :
92520989
Full Text :
https://doi.org/10.1016/j.reprotox.2013.08.007