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An immunoglobulin role for the CD8 beta chain.

Authors :
Wheeler, C.J.
von Hoegen, P.
Source :
Nature. 5/21/1992, Vol. 357 Issue 6375, p247. 3p. 1 Chart, 15 Graphs.
Publication Year :
1992

Abstract

Shows that CD8alpha beta transfectants produce more interleukin-2 than CD8alpha transfectants in response to specific stimuli. Functional division of mature T cells by surface expression of either CD4 or CD8; Thymic selection; Demonstration of a significant difference in the responsiveness of CD8alpha beta versus CD8 alpha transfectants to specific T-cell antigen receptor (TCR)-mediated responses.

Subjects

Subjects :
*CELLS

Details

Language :
English
ISSN :
00280836
Volume :
357
Issue :
6375
Database :
Academic Search Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
9207205200
Full Text :
https://doi.org/10.1038/357247a0