The effect of injection of EGb 761 into the lateral ventricle on hippocampal cell apoptosis and stem cell stimulation in situ of the ischemic/reperfusion rat model.

Highlights: [•] EGb 761 treatment significantly reduced the infarct volume. [•] EGb 761 decreased ischemia-induced apoptosis in ipsilateral cortex and hippocampus. [•] Neurogenesis in the hippocampus was enhanced by EGb 761 treatment. [•] The colocalization of PSA-NCAM and BrdU was enhanced by EGb 761 treatment. [ABSTRACT FROM AUTHOR]