Asthma and Coagulation.

The article discusses research which examined correlation between protease allergen and toll-like receptor (TLR4) signaling. It references a study conducted by V. O. Millien and colleagues, published in a 2013 issue of "Science" journal. It describes critical role of TLR4 in allergic response of individuals to fungal proteases. Research authors have concluded that inhalation of an aspergillus protease usually depends on TLR4 activity and downstream adaptor molecules.