A facile synthesis of 4- and 6-chloromethyl-1H-indole-2-carboxylates: replacement of a sulfonic acid functionality by chlorine

Authors :: Pete, Béla
Parlagh, Gyula
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2003, Vol. 44 Issue 12, p2537. 3p.
Publication Year :: 2003
Abstract: Valuable new synthetic intermediates, 4- or 6-chloromethyl-1H-indole-2-carboxylates, were prepared by the elimination of SO2 from 2-ethoxycarbonyl-1H-indole-4- or 6-methanesulfonic acids, respectively, which are easily accessible by Fischer-type indolization. [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 44
Issue :: 12
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 9189438
Full Text :: https://doi.org/10.1016/S0040-4039(03)00327-7

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