Potential Regulatory Interactions of Escherichia coli RraA Protein with DEAD-box Helicases.

Background: DEAD-box helicases in bacteria play a key role in cellular RNA metabolism. Results: The trimeric protein RraA binds to Escherichia coli DEAD-box proteins. Conclusion: The mechanism of interaction between RraA and SrmB is shown by x-ray crystallography. Significance: Structural basis of potential regulation of a bacterial DEAD-box helicase. [ABSTRACT FROM AUTHOR]