Back to Search Start Over

Two-dimensional hybrid mesoporous Fe2O3–graphene nanostructures: A highly active and reusable peroxidase mimetic toward rapid, highly sensitive optical detection of glucose.

Authors :
Xing, Zhicai
Tian, Jingqi
Asiri, Abdullah M.
Qusti, Abdullah H.
Al-Youbi, Abdulrahman O.
Sun, Xuping
Source :
Biosensors & Bioelectronics. Feb2014, Vol. 52, p452-457. 6p.
Publication Year :
2014

Abstract

Abstract: In this article, for the first time, two-dimensional hybrid mesoporous Fe2O3–graphene (mFe2O3–G) nanostructures were developed as a peroxidase mimetic with catalytic activities superior to those of mFe2O3, G, and previously reported Fe-based peroxidase mimetics. The high-surface-area mFe2O3 not only offers a large number of catalytically active sites, but also facilitates the diffusion of 3,3,5,5-tetramethylbenzidine (TMB) and H2O2 toward G surface. On the other hand, G is π-rich and thus favors the adsorption and enrichment of TMB within these pores. These synergistic effects lead to highly improved catalytic performances. Based on these findings, a simple, rapid, and highly sensitive and selective optical detector of glucose has been developed and demonstrated in buffer solution with a pretty low detection limit of 0.5μM. In addition, this nanosensor is reusable and can also be used for glucose detection in diluted serum. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
09565663
Volume :
52
Database :
Academic Search Index
Journal :
Biosensors & Bioelectronics
Publication Type :
Academic Journal
Accession number :
91739218
Full Text :
https://doi.org/10.1016/j.bios.2013.09.029