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Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish.

Authors :
Ryan, Sean
Willer, Jason
Marjoram, Lindsay
Bagwell, Jennifer
Mankiewicz, Jamie
Leshchiner, Ignaty
Goessling, Wolfram
Bagnat, Michel
Katsanis, Nicholas
Source :
Development (09501991). 11/1/2013, Vol. 140 Issue 21, p4445-4451. 7p.
Publication Year :
2013

Abstract

The article presents a study on genetic approaches for the rapid identification of kidney cyst mutations in zebrafish, with information on the process of whole exome sequencing to identify genetic mutations. Topics include the whole exome sequencing (WES) method for the isolation of genetic code; research on the causality of genetic disorders in humans; and genome sequencing for the identification of mutations.

Details

Language :
English
ISSN :
09501991
Volume :
140
Issue :
21
Database :
Academic Search Index
Journal :
Development (09501991)
Publication Type :
Academic Journal
Accession number :
91606181
Full Text :
https://doi.org/10.1242/dev.101170