Antimicrobial peptides and induced membrane curvature: Geometry, coordination chemistry, and molecular engineering.

Highlights: [•] AMPs are multifunctional molecules that selectively permeate microbial membranes. [•] Negative Gaussian curvature (NGC) enables many types of membrane permeation. [•] NGC generation by AMPs constrains their compositions in the form of a general rule. [•] We show that the sequences of known cationic AMPs are consistent with this rule. [ABSTRACT FROM AUTHOR]